Description

3-Amino-6-Fluoropyridazine is a versatile fluorinated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its bifunctional structure, featuring both an amino group and a fluorine atom on a pyridazine ring, enabling precise molecular modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals, organic semiconductors, and fluorinated polymers.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes and tags to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	3-Amino-6-Fluoropyridazine
CAS No.	108784-42-5
Molecular Formula	C4H4FN3
Molecular Weight	113.09 g/mol
Synonyms	6-Fluoro-3-pyridazinamine; 6-Fluoro-3-aminopyridazine; 3-Amino-6-fluoropyridazine; 6-Fluoro-pyridazin-3-ylamine; 3-Pyridazinamine, 6-fluoro-; 108784-42-5; FC1=CC=NN=C1N
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Fluoropyridazine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.