Description

Menthyl 3-Hydroxybutyrate is a chiral ester compound valued for its unique organoleptic and functional properties. This specialty chemical serves as a versatile intermediate and active ingredient, offering solutions for product formulation and synthesis where specific stereochemistry and mild, cooling characteristics are required. Key industries that utilize this compound include flavor & fragrance, personal care, and advanced pharmaceutical synthesis.

Application

• Flavor & Fragrance Industry: Used as a cooling agent and flavor modifier in mint, menthol, and other fresh-taste profiles for confectionery, oral care, and beverages.
• Personal Care & Cosmetics: Incorporated into formulations for its soothing and cooling sensation in products like lip balms, aftershaves, muscle rubs, and topical creams.
• Pharmaceutical Intermediates: Serves as a chiral building block in the synthesis of more complex active pharmaceutical ingredients (APIs) due to its defined stereochemistry.
• Advanced Polymer Additives: Acts as a monomer or plasticizer modifier in specialty polymer systems to impart specific physical properties.
• Chemical Synthesis: Employed as a reagent or protecting group in organic synthesis, particularly in stereoselective reactions.

Basic Information

Product Name	Menthyl 3-Hydroxybutyrate
CAS No.	108766-16-1
Molecular Formula	C₁₄H₂₆O₃
Molecular Weight	242.36 g/mol
Synonyms	(-)-Menthyl (R)-3-Hydroxybutyrate; L-Menthyl 3-Hydroxybutyrate; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 3-hydroxybutanoate; 3-Hydroxybutyric Acid Menthyl Ester; Menthol 3-Hydroxybutyrate; p-Menth-3-yl 3-hydroxybutyrate; Cooling Agent 108766-16-1
EINECS	Contact for details

Quality Control

Our Menthyl 3-Hydroxybutyrate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, enantiomeric excess, and impurity profiles. Specifications can be aligned with customer requirements for food-grade, cosmetic-grade, or pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and excessive heat.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	-50° to -55° (c=1 in CHCl₃)
Refractive Index (20°C)	1.465 - 1.475
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.