Description

5-(2-Thienyl)Tetrahydrothiophen-3-One is a specialized heterocyclic organic compound featuring fused thiophene and tetrahydrothiophenone rings. This unique molecular architecture makes it a valuable and versatile building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and functional materials. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex sulfur-containing molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or insecticides where the thienyl-tetrahydrothiophenone scaffold contributes to biological activity.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing advanced polymers, ligands for catalysis, or organic electronic materials with tailored properties.
• Chemical Research: Employed in academic and industrial R&D for methodological studies in heterocyclic chemistry, asymmetric synthesis, and the development of new synthetic routes.
• Ligand and Catalyst Development: The sulfur and carbonyl functionalities make it a useful starting point for designing novel chelating ligands or organocatalysts.

Basic Information

Product Name	5-(2-Thienyl)Tetrahydrothiophen-3-One
CAS No.	108372-48-1
Molecular Formula	C8H8OS2
Molecular Weight	184.28 g/mol
Synonyms	3-Thiophen-2-yltetrahydrothiophen-5-one; 2-(3-Oxotetrahydrothiophen-5-yl)thiophene; 5-(Thiophen-2-yl)tetrahydrothiophen-3-one; 3-Thiophen-2-yltetrahydrothiophen-5-one; Tetrahydro-5-(2-thienyl)-3(2H)-thiophenone
EINECS	Contact for details

Quality Control

Our 5-(2-Thienyl)Tetrahydrothiophen-3-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor purity grades to meet specific project requirements, from research to pilot-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.