Description

8-Hydroxy-3,6-dioxaoctanal is a versatile bifunctional chemical building block featuring both a reactive aldehyde group and a terminal hydroxyl group, separated by a polyether chain. This unique structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and specialty chemical sectors. It is primarily sought after by research chemists and process development scientists for applications in drug discovery, polymer modification, and the creation of novel cross-linking agents.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), prodrugs, and drug conjugates.
• Polymer & Material Science: Used as a monomer or cross-linker for producing specialty polyethers, hydrogels, and functionalized polymers with tailored properties.
• Bioconjugation & Linker Chemistry: Facilitates the attachment of biomolecules (e.g., peptides, proteins) to other entities like dyes, drugs, or solid supports.
• Surface Modification: Employed to introduce hydrophilic polyether chains onto surfaces, enhancing biocompatibility or altering surface energy.
• Ligand & Chelator Synthesis: Serves as a precursor for creating complexing agents and ligands used in catalysis or metal ion sequestration.
• Fine Chemical Synthesis: A versatile synthon for constructing heterocycles and other complex organic molecules in research and development.

Basic Information

Product Name	8-Hydroxy-3,6-dioxaoctanal
CAS No.	108306-81-6
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	3,6-Dioxa-8-hydroxyoctanal; 8-Hydroxy-3,6-dioxaoctanaldehyde; 2-[2-(2-Hydroxyethoxy)ethoxy]acetaldehyde; Poly(ethylene glycol) monoaldehyde; PEG monoaldehyde (n=2); HO-PEG2-CHO; 8-Hydroxy-3,6-dioxaoctan-1-al
EINECS	Contact for details

Quality Control

Our 8-Hydroxy-3,6-dioxaoctanal is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR and NMR, and quantification of key impurities. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment to ensure it meets your precise research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. Due to its sensitivity to oxidation, prolonged exposure to air should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.