Description

1-Bromo-2-Chlorobutane is a versatile halogenated alkane intermediate of significant importance in synthetic organic chemistry. Its bifunctional nature, featuring both bromine and chlorine atoms, makes it a valuable building block for constructing more complex molecular architectures. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications such as alkylation and as a precursor in multi-step synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Agrochemical Synthesis: Used as an intermediate in the production of herbicides, pesticides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in alkylation reactions, Grignard reagent formation, and as a precursor for other functionalized butane derivatives.
• Liquid Crystal & Material Science: Serves as a starting material in the synthesis of organic compounds for advanced materials and liquid crystal displays (LCDs).
• Chemical Research & Development: Utilized in academic and industrial R&D for method development and exploring new synthetic pathways.
• Cross-Coupling Reactions: Acts as a substrate in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	1-Bromo-2-Chlorobutane
CAS No.	108200-18-6
Molecular Formula	C4H8BrCl
Molecular Weight	171.46 g/mol
Synonyms	2-Chloro-1-bromobutane; Butane, 1-bromo-2-chloro-; 1-Bromo-2-chlorobutane; 2-Chlorobutyl bromide; NSC 60545; α-Bromo-β-chlorobutane
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chlorobutane is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and reliability. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reactive metals. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	~1.45 g/cm³
Boiling Point	~155-160°C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.