Description

Hydroxyalbendazole is a key pharmaceutical intermediate and metabolite of the broad-spectrum anthelmintic agent Albendazole. This compound is critical for research and development in veterinary and human parasitology, offering a pathway to study drug efficacy, metabolism, and resistance. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories focused on developing and quality-controlling antiparasitic formulations.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of Albendazole and related anthelmintic drugs.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and bioequivalence studies for Albendazole.
• Veterinary Medicine Research: Employed in R&D for developing new formulations and combination therapies against parasitic infections in livestock.
• Human Antiparasitic Drug Development: Aids in the research of next-generation treatments for helminth infections.
• Quality Control & Analytical Testing: Essential for HPLC, LC-MS, and other chromatographic methods to assay purity and content in finished drug products.
• Stability Studies: Used to identify and quantify degradation products in Albendazole-based pharmaceuticals.

Basic Information

Product Name	Hydroxyalbendazole
CAS No.	107966-05-2
Molecular Formula	C12H15N3O3S
Molecular Weight	281.33 g/mol
Synonyms	Albendazole Hydroxide; Albendazole Metabolite; Albendazole-OH; 2-[(Propylthio)-1H-benzimidazol-5-yl]methanol; 5-(Hydroxymethyl)-2-propylthio-1H-benzimidazole; 5-(Hydroxymethyl)-1H-benzimidazol-2-yl propyl sulfide; Albendazole Sulfoxide (related metabolite); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our Hydroxyalbendazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets high-grade standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.