Description

2-Amino-4-(4-Fluorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is a high-value, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical and agrochemical agents, offering a versatile scaffold for structural diversification. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating libraries of bioactive molecules and developing new synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Organic Synthesis Scaffold: Utilized in multicomponent reactions (MCRs) and cyclization reactions to construct complex polyheterocyclic systems.
• Chemical Biology Probe Development: Acts as a core structure for creating fluorescent dyes or molecular probes to study biological processes.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting fundamental research in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Amino-4-(4-Fluorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile
CAS No.	107752-99-8
Molecular Formula	C18H17FN2O2
Molecular Weight	312.34 g/mol
Synonyms	2-Amino-4-(4-fluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4H-Chromene-3-carbonitrile, 2-amino-4-(4-fluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-; 2-Amino-4-(p-fluorophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; 4-(4-Fluorophenyl)-2-amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile; Tetrahydrochromene Carbonitrile Derivative; Fluorophenyl Tetrahydrochromene Carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Fluorophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.