Description

Ethyl 2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate is a high-value, multi-functional heterocyclic building block with significant synthetic utility. This compound matters for its role as a versatile precursor in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel chromene and pyran derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and microbial infections.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its chromene core structure for bioactivity.
• Organic Synthesis Building Block: A versatile synthon for constructing complex polycyclic frameworks via cyclization and condensation reactions.
• Material Science Research: Investigated as a precursor for organic electronic materials and fluorescent dyes due to its conjugated chromene system.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Catalysis & Ligand Development: Potential use in developing novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Item	Details
Product Name	Ethyl 2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate
CAS No.	107752-96-5
Molecular Formula	C20H22BrNO4
Molecular Weight	420.30 g/mol
Synonyms	Ethyl 2-Amino-4-(4-bromophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate; 4H-Chromene-3-carboxylic acid, 2-amino-4-(4-bromophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-, ethyl ester; 2-Amino-4-(4-bromophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylic acid ethyl ester; 4-(4-Bromophenyl)-2-amino-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylic acid ethyl ester; Chromene derivative CAS 107752-96-5
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-(4-Bromophenyl)-7,7-Dimethyl-5-Oxo-5,6,7,8-Tetrahydro-4H-Chromene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO principles ensures reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.