Description

Ethanone, 1-(3-Chloro-3-Methylcyclobutyl)-, trans- (9Ci) is a specialized organic building block featuring a unique cyclobutyl ring structure substituted with chloro and methyl groups. This compound is valued for its role as a key chiral intermediate in advanced pharmaceutical synthesis and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its substituted cyclobutane core contributes to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with tailored thermal and mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Ethanone, 1-(3-Chloro-3-Methylcyclobutyl)-, trans- (9Ci)
CAS No.	107693-35-6
Molecular Formula	C7H11ClO
Molecular Weight	146.61 g/mol
Synonyms	trans-1-(3-Chloro-3-methylcyclobutyl)ethanone; 1-(3-Chloro-3-methylcyclobutyl)ethan-1-one; 3-Chloro-3-methylcyclobutyl methyl ketone; (trans)-3'-Chloro-3'-methylcyclobutyl methyl ketone; 107693-35-6; Ethanone, 1-(3-chloro-3-methylcyclobutyl)-, (1R,3R)-rel-; (1R,3R)-rel-1-(3-Chloro-3-methylcyclobutyl)ethanone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-value intermediate. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, and each batch is analyzed to meet precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 98.0% (by GC or NMR)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.