Description

Ethanone, 1-(3-Hydroxy-3-Methylcyclobutyl)-, trans- (9Ci) is a specialized organic compound featuring a cyclobutyl ring substituted with hydroxyl and methyl groups, linked to an ethanone moiety. This unique structure makes it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and fine chemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Asymmetric Synthesis: Serves as a precursor for ligands, catalysts, or complex fragments requiring the defined stereochemistry of the trans-configured cyclobutane ring.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials where its rigid ring structure imparts specific properties.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for constructing challenging carbon frameworks.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing novel aroma chemicals with unique olfactory characteristics derived from its ketone and alcohol functionalities.

Basic Information

Product Name	Ethanone, 1-(3-Hydroxy-3-Methylcyclobutyl)-, trans- (9Ci)
CAS No.	107693-34-5
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	trans-1-(3-Hydroxy-3-methylcyclobutyl)ethanone; 1-(3-Hydroxy-3-methylcyclobutyl)ethanone, trans-; 3-Methyl-3-hydroxycyclobutyl methyl ketone; (1R,3S)-1-(3-Hydroxy-3-methylcyclobutyl)ethan-1-one (enantiomer); (1S,3R)-1-(3-Hydroxy-3-methylcyclobutyl)ethan-1-one (enantiomer); 3-Hydroxy-3-methylcyclobutan-1-yl methyl ketone; trans-3-Hydroxy-3-methylcyclobutyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(3-Hydroxy-3-Methylcyclobutyl)-, trans- (9Ci) adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, with a focus on chiral purity where specified. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing parameters such as assay (by GC/HPLC), enantiomeric excess (by chiral HPLC), and impurity profiles. We support cGMP-compliant documentation for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when required for synthesis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (for chiral-specific grade)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.