Description

4-Chloro-n-[4-(Trifluoromethyl)Phenyl]Benzenesulfonamide CAS NO 107491-59-8 is a specialized sulfonamide derivative, a key chemical intermediate prized for its unique trifluoromethyl and chlorophenyl functional groups. This compound matters for its role in synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where it contributes to the development of active ingredients with enhanced biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers engaged in the development of novel therapeutic agents, crop protection chemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic or inflammatory pathways.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the sulfonamide and trifluoromethyl groups.
• Material Science: Serves as a precursor for advanced polymers and liquid crystals, where its aromatic and halogenated structure can impart specific thermal and optical properties.
• Organic Synthesis: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D laboratories.
• Biochemical Probe Development: Utilized in medicinal chemistry to create tool compounds for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	4-Chloro-n-[4-(Trifluoromethyl)Phenyl]Benzenesulfonamide
CAS No.	107491-59-8
Molecular Formula	C13H9ClF3NO2S
Molecular Weight	335.73 g/mol
Synonyms	4-Chloro-N-[4-(trifluoromethyl)phenyl]benzenesulfonamide; Benzenesulfonamide, 4-chloro-N-[4-(trifluoromethyl)phenyl]-; 4-Chloro-N-(4-trifluoromethylphenyl)benzenesulfonamide; 4-Chloro-N-(alpha,alpha,α-trifluoro-p-tolyl)benzenesulfonamide; N-(4-Chlorophenylsulfonyl)-4-(trifluoromethyl)aniline; 107491-59-8; TFCPS; p-Chloro-N-(p-trifluoromethylphenyl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-Chloro-n-[4-(Trifluoromethyl)Phenyl]Benzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.