Description

2-(3-Hydroxyphenoxy)-Acetonitrile is a versatile phenolic nitrile derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of high-value fine chemicals and active pharmaceutical ingredients (APIs). Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty polymer production need this high-purity intermediate to develop new compounds with specific functional properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a phenolic ether linkage.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Liquid Crystal & Electronic Materials: Used in the production of specialty monomers for high-performance polymers and liquid crystal displays (LCDs).
• Dye & Pigment Manufacturing: Intermediate for synthesizing complex organic dyes and pigments, especially azo and anthraquinone derivatives.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Research & Development: Essential chemical for academic and industrial R&D labs exploring new synthetic methodologies and material science.

Basic Information

Product Name	2-(3-Hydroxyphenoxy)-Acetonitrile
CAS No.	107223-69-8
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	3-Hydroxyphenoxyacetonitrile; (3-Hydroxyphenoxy)acetonitrile; 2-(3-Hydroxyphenoxy)ethanenitrile; Acetonitrile, 2-(3-hydroxyphenoxy)-; m-Hydroxyphenoxyacetonitrile; 3-Hydroxy-phenoxy-acetonitrile; 107223-69-8 (CAS); Glycolonitrile, 3-hydroxyphenyl ether
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxyphenoxy)-Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.