Description

(S)-Ethyl 4-Benzyl-5-Oxo-Morpholine-3-Carboxylate is a high-value, chiral morpholine derivative serving as a critical synthetic intermediate in advanced organic synthesis. Its defined stereochemistry and functionalized ring system make it an essential building block for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Synthesis: Employed as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of complex, high-value agrochemicals and specialty chemicals.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in CRO/CMO settings.

Basic Information

Product Name	(S)-Ethyl 4-Benzyl-5-Oxo-Morpholine-3-Carboxylate
CAS No.	106973-40-4
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	(3S)-4-Benzyl-3-(ethoxycarbonyl)morpholin-2-one; Ethyl (S)-4-benzyl-2-oxo-1,4-morpholine-3-carboxylate; (S)-4-Benzyl-3-ethoxycarbonylmorpholin-2-one; (S)-Ethyl 4-benzyl-5-oxomorpholine-3-carboxylate; 4-Benzyl-2-oxo-3-morpholinecarboxylic acid ethyl ester, (3S)-; (S)-4-Benzyl-3-(ethoxycarbonyl)-2-morpholinone; 106973-40-4; (S)-4-Benzyl-3-(ethoxycarbonyl)-3,4-dihydro-2H-1,4-oxazin-2-one
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 4-Benzyl-5-Oxo-Morpholine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, enantiomeric excess, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.