Description

4-Amino-3-Iodobenzylguanidine is a specialized iodinated aromatic guanidine derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and precursor for the synthesis of targeted therapeutic agents and diagnostic probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology, neurology, and radiopharmaceutical development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neuroendocrine tumors and neurological disorders.
• Radiopharmaceutical Development: Serves as a backbone for labeling with radioactive iodine isotopes (e.g., I-123, I-131) to create targeted imaging and therapeutic agents.
• Biochemical Research: Used as a tool compound in studies involving guanidine transporters, adrenergic receptors, and cellular uptake mechanisms.
• Precision Medicine: Enables the development of targeted therapies through its incorporation into molecules designed for specific biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and pharmacological studies.

Basic Information

Product Name	4-Amino-3-Iodobenzylguanidine
CAS No.	106941-20-2
Molecular Formula	C8H11IN4
Molecular Weight	290.10 g/mol
Synonyms	3-Iodo-4-aminobenzylguanidine; AIBG; 4-Amino-3-iodo-benzylguanidine; 1-(4-Amino-3-iodobenzyl)guanidine; Benzylguanidine, 4-amino-3-iodo-; Guanidine, N-(4-amino-3-iodobenzyl)-
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Iodobenzylguanidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports applications requiring research-grade to GMP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.