Description

(S)-4-Benzyl-5-Oxomorpholine-3-Carboxylic Acid is a high-purity chiral building block and advanced pharmaceutical intermediate of significant commercial importance. Its stereochemically defined structure makes it a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the production of novel therapeutics and high-value specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis Building Block: Employed in the construction of complex molecules requiring high enantiomeric purity, leveraging its morpholine-3-carboxylic acid core.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization in drug discovery programs.
• Peptidomimetic Development: Serves as a constrained scaffold in the design and synthesis of peptidomimetics and protease inhibitors.
• Catalyst and Ligand Synthesis: A precursor for developing novel chiral catalysts and ligands used in asymmetric transformations.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-4-Benzyl-5-Oxomorpholine-3-Carboxylic Acid
CAS No.	106910-79-6
Molecular Formula	C12H13NO4
Molecular Weight	235.24 g/mol
Synonyms	(3S)-4-Benzyl-5-oxomorpholine-3-carboxylic acid; (S)-4-Benzyl-5-oxo-3-morpholinecarboxylic acid; (S)-4-Benzylmorpholine-3,5-dione-3-carboxylic acid; L-4-Benzyl-2,3-dioxomorpholine-3-carboxylic acid; (S)-4-Benzyl-2,3-dioxo-1,4-oxazinane-3-carboxylic acid; 4-Benzyl-5-oxo-3-morpholinecarboxylic acid, (S)-; 106910-79-6; (S)-4-Bn-5-oxomorpholine-3-COOH
EINECS	Contact for details

Quality Control

Our (S)-4-Benzyl-5-Oxomorpholine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.