Description

5-Methyl-2-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring a trifluoromethyl substituent, which imparts unique physicochemical properties critical for advanced chemical synthesis. This compound serves as a high-value building block in the development of complex molecules, offering enhanced metabolic stability and lipophilicity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transporting layers in organic light-emitting diodes (OLEDs) and display technologies.
• Dye & Pigment Manufacturing: Employed in the production of specialized azo dyes and high-performance pigments requiring specific light-fastness and color properties.
• Polymer & Resin Modifier: Acts as a monomer or curing agent in the synthesis of specialty polymers, including polyimides and epoxy resins, to modify thermal and chemical resistance.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex heterocycles and fluorinated compounds in medicinal chemistry projects.

Basic Information

Product Name	5-Methyl-2-(Trifluoromethyl)Aniline
CAS No.	106877-29-6
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	2-Amino-α,α,α-trifluoro-p-xylene; 2-Trifluoromethyl-5-methylaniline; 5-Methyl-2-(trifluoromethyl)benzenamine; 2-Amino-5-methylbenzotrifluoride; α,α,α-Trifluoro-5-methyl-o-toluidine; 2-(Trifluoromethyl)-5-methylphenylamine; 5-Methyl-α,α,α-trifluoro-o-toluidine; Benzenamine, 5-methyl-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-2-(Trifluoromethyl)Aniline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee supply chain transparency and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure containers are kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.