Description

1H-1,2,4-Triazole-5-Carboxylicacid,1-Methyl-,Hydrazide(9Ci) CAS NO 106535-36-8 is a specialized heterocyclic building block featuring a triazole core functionalized with a methyl group and a carboxylic acid hydrazide moiety. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting enzymes or receptors where the triazole scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, or plant growth regulators that incorporate heterocyclic structures for enhanced efficacy.
• Ligand and Chelator Preparation: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis due to its nitrogen-rich structure.
• Material Science Research: Employed in the synthesis of polymers or organic electronic materials where the triazole unit can modify material properties.
• Bioconjugation Chemistry: The reactive hydrazide group can be utilized for linking molecules to proteins, antibodies, or other biomolecules in diagnostic or therapeutic applications.
• Academic & Industrial R&D: A valuable building block for medicinal chemistry programs and exploratory synthetic chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	1H-1,2,4-Triazole-5-Carboxylicacid,1-Methyl-,Hydrazide(9Ci)
CAS No.	106535-36-8
Molecular Formula	C4H7N5O
Molecular Weight	141.13 g/mol
Synonyms	1-Methyl-1H-1,2,4-triazole-5-carboxylic acid hydrazide; 1-Methyl-1,2,4-triazole-5-carbohydrazide; 5-Hydrazinylcarbonyl-1-methyl-1,2,4-triazole; 1-Methyl-1H-1,2,4-triazole-5-carbohydrazide; 1-Methyl-1,2,4-triazol-5-ylcarboxylic acid hydrazide; 1-Methyl-5-(hydrazinecarbonyl)-1H-1,2,4-triazole; 106535-36-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 1H-1,2,4-Triazole-5-Carboxylicacid,1-Methyl-,Hydrazide(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary packaging or amber glass. For long-term storage, consider maintaining the material under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.