Description

6-Methoxy-2,5,7,8-Tetramethyl-Chroman-2-Carboxylic Acid is a high-purity synthetic antioxidant and a key intermediate in the production of advanced pharmaceutical and nutraceutical compounds. This compound is valued for its potent free radical scavenging properties and structural role as a precursor to Vitamin E analogs and other tocopherol derivatives. It is essential for manufacturers in the pharmaceutical, dietary supplement, and specialty chemical industries seeking reliable, high-quality raw materials for synthesis and formulation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of tocopherols (Vitamin E) and other chroman-based therapeutic agents.
• Antioxidant Research & Development: Used as a reference standard and active component in studies focused on oxidative stress and lipid peroxidation.
• Nutraceutical Formulations: Incorporated into high-end dietary supplements and functional food products for its antioxidant benefits.
• Cosmetic & Personal Care: Employed in stabilizing formulations for creams, serums, and lotions that require protection against oxidation.
• Polymer & Material Science: Acts as a stabilizer additive in plastics and synthetic materials to prevent degradation from heat and light.
• Fine Chemical Synthesis: Serves as a versatile chiral intermediate for the preparation of more complex organic molecules in agrochemical and specialty chemical production.

Basic Information

Product Name	6-Methoxy-2,5,7,8-Tetramethyl-Chroman-2-Carboxylic Acid
CAS No.	106461-96-5
Molecular Formula	C16H22O4
Molecular Weight	278.34 g/mol
Synonyms	6-Methoxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; 2-Carboxy-2,5,7,8-tetramethyl-6-methoxychroman; 6-Methoxy-Trolox; Trolox Methyl Ether; Chroman-2-carboxylic acid, 6-methoxy-2,5,7,8-tetramethyl-; 2H-1-Benzopyran-2-carboxylic acid, 6-methoxy-2,5,7,8-tetramethyl-3,4-dihydro-; Antioxidant intermediate 106461-96-5
EINECS	Contact for details

Quality Control

Our 6-Methoxy-2,5,7,8-Tetramethyl-Chroman-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.