Description

6-Chloro-2-Methyl-3,4-Dihydro-2H-1-Benzopyran-2-Acetic Acid is a high-purity, synthetically derived chroman derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique fused ring structure, which provides a versatile scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the creation of novel therapeutic agents, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the synthesis of advanced herbicides, fungicides, and plant growth regulators, leveraging its chlorinated chroman core.
• Organic Chemistry Research: A valuable substrate for methodological studies in asymmetric synthesis, ring-forming reactions, and the exploration of new catalytic processes.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, including dyes, pigments, and advanced materials requiring specific chroman-based architectures.
• Biochemical Tool Compound: Potential use in biochemical assays and as a starting point for developing enzyme inhibitors or receptor modulators in discovery programs.

Basic Information

Product Name	6-Chloro-2-Methyl-3,4-Dihydro-2H-1-Benzopyran-2-Acetic Acid
CAS No.	106430-26-6
Molecular Formula	C₁₂H₁₃ClO₃
Molecular Weight	240.68 g/mol
Synonyms	6-Chloro-2-methylchroman-2-acetic acid; 2-(6-Chloro-2-methyl-3,4-dihydro-2H-chromen-2-yl)acetic acid; 6-Chloro-2-methyl-2-carboxymethylchroman; 6-Chloro-2-methyl-3,4-dihydro-2H-1-benzopyran-2-acetic acid; (6-Chloro-2-methyl-3,4-dihydro-2H-chromen-2-yl)acetic acid; Chroman-2-acetic acid, 6-chloro-2-methyl-; 106430-26-6 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Methyl-3,4-Dihydro-2H-1-Benzopyran-2-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.