Description

Ethylmethylglyoxal Bis(Guanylhydrazone) is a specialized guanylhydrazone derivative with significant biological activity. This compound is valued for its role as a potent inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the polyamine biosynthesis pathway. It is primarily utilized by researchers and developers in the pharmaceutical and life sciences sectors for biochemical research, enzyme inhibition studies, and the development of therapeutic agents targeting polyamine metabolism.

Application

• Biochemical Research: Used as a specific inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC) in enzymatic and cellular studies.
• Pharmaceutical Development: Investigated as a potential lead compound or tool molecule for developing antiproliferative and anticancer agents.
• Polyamine Pathway Studies: Essential for research focused on understanding the regulation and function of polyamine biosynthesis in various biological systems.
• Cell Culture & In Vitro Assays: Employed to modulate intracellular polyamine levels and study their effects on cell growth, differentiation, and apoptosis.
• Life Science Reagents: Serves as a high-purity reference standard and active ingredient in specialized research kits and biochemical reagents.

Basic Information

Product Name	Ethylmethylglyoxal Bis(Guanylhydrazone)
CAS No.	106119-99-7
Molecular Formula	C8H20N8O2
Molecular Weight	260.30 g/mol
Synonyms	EMGBG; Ethylmethylglyoxal bis(guanylhydrazone); 1,1'-[(1E,2E)-1-Ethyl-2-methyl-1,2-ethanediylidene]bis[2-(diaminomethylene)hydrazine]; AdoMetDC Inhibitor EMGBG; S-Adenosylmethionine Decarboxylase Inhibitor; NSC 329854; Bis(guanylhydrazone) of Ethylmethylglyoxal
EINECS	Contact for details

Quality Control

Our Ethylmethylglyoxal Bis(Guanylhydrazone) is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is analyzed using advanced techniques including HPLC and NMR to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.