Description

1,2-Dihydro-2-(Iodomethyl)-Naphthalene CAS NO 105812-53-1 is a specialized organic iodide derivative of naphthalene, serving as a versatile building block in advanced chemical synthesis. Its value lies in the reactive iodomethyl group, which facilitates efficient carbon-carbon and carbon-heteroatom bond formation under mild conditions. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the construction of tetralin-based and other fused polycyclic frameworks present in various therapeutic agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific halogenated naphthalene motifs.
• Material Science: Acts as a precursor for functionalized organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: Serves as an efficient electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to introduce the naphthylmethyl moiety.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and radical reactions to incorporate the 2-(iodomethyl)-1,2-dihydronaphthalene unit into target molecules.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the carbon-iodine bond.

Basic Information

Item	Details
Product Name	1,2-Dihydro-2-(Iodomethyl)-Naphthalene
CAS No.	105812-53-1
Molecular Formula	C11H11I
Molecular Weight	270.11 g/mol
Synonyms	2-(Iodomethyl)-1,2-dihydronaphthalene; 1,2-Dihydro-2-iodomethylnaphthalene; 2-Iodomethyl-1,2-dihydronaphthalene; Naphthalene, 1,2-dihydro-2-(iodomethyl)-; (1,2-Dihydronaphthalen-2-yl)methyl iodide
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-2-(Iodomethyl)-Naphthalene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and organic iodide content, the container should be kept away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.