Description

2H-Pyran, Tetrahydro-4-(Nitromethylene)- is a specialized nitroalkene derivative with a tetrahydro-2H-pyran scaffold, serving as a valuable synthetic intermediate. Its core value lies in its unique reactivity profile, where the nitromethylene group adjacent to the heterocyclic ring acts as a versatile handle for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for constructing complex heterocyclic cores and introducing functional diversity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive nitromethylene group for carbon-carbon bond formation.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and functional materials requiring specific nitro-olefin chemistry.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, including cycloaddition reactions and nucleophilic addition studies.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers with tailored properties.

Basic Information

Product Name	2H-Pyran, Tetrahydro-4-(Nitromethylene)-
CAS No.	105772-10-9
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	4-(Nitromethylene)tetrahydro-2H-pyran; Tetrahydro-4-(nitromethylene)-2H-pyran; 4-Nitromethylenetetrahydropyran; 3,4,5,6-Tetrahydro-4-(nitromethylene)-2H-pyran; 2H-Pyran, tetrahydro-4-(nitromethylene)-; 4-(Nitromethylene)tetrahydropyran
EINECS	Contact for details

Quality Control

Our 2H-Pyran, Tetrahydro-4-(Nitromethylene)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to prolonged exposure to air and moisture; therefore, containers should be kept sealed under an inert atmosphere after opening.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.