Description

(2R,3S)-3,4-Dihydro-2-(3-Hydroxy-4-Methoxyphenyl)-5,7-Dimethoxy-2H-1-Benzopyran-3-Ol CAS NO 105330-59-4 is a high-purity, stereochemically defined flavan derivative, a key structural motif in natural polyphenols. This compound is valued for its role as a critical chiral intermediate and reference standard in advanced pharmaceutical and nutraceutical research. It is primarily sought by R&D and quality control laboratories in the pharmaceutical, biotechnology, and natural product sectors for developing and standardizing bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel therapeutic agents targeting oxidative stress and inflammation.
• Reference Standard: Used in analytical laboratories for the identification, method development, and quantification of flavanoids and related polyphenolic compounds via HPLC, LC-MS, or NMR.
• Nutraceutical Research: Employed in the study and development of high-value dietary supplements and functional foods for their potential antioxidant properties.
• Biochemical Research: Acts as a precise tool in enzymology and metabolic pathway studies to investigate the biological activity of specific flavan stereoisomers.
• Cosmeceutical Development: Utilized in R&D for formulating advanced skincare products aimed at providing antioxidant and anti-aging benefits.

Basic Information

Product Name	(2R,3S)-3,4-Dihydro-2-(3-Hydroxy-4-Methoxyphenyl)-5,7-Dimethoxy-2H-1-Benzopyran-3-Ol
CAS No.	105330-59-4
Molecular Formula	C19H20O6
Molecular Weight	344.36 g/mol
Synonyms	(2R,3S)-3',4',5,7-Tetramethoxyflavan-3-ol; (2R,3S)-5,7-Dimethoxy-3',4'-dimethoxyflavan-3-ol; (2R,3S)-3,4-Dihydro-2-(3-hydroxy-4-methoxyphenyl)-5,7-dimethoxy-2H-1-benzopyran-3-ol; A specific stereoisomer of Tetramethoxyflavan-3-ol; Flavan-3-ol derivative
EINECS	Contact for details

Quality Control

Every batch of our (2R,3S)-3,4-Dihydro-2-(3-Hydroxy-4-Methoxyphenyl)-5,7-Dimethoxy-2H-1-Benzopyran-3-Ol is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, typically including HPLC for assay and chiral purity, NMR, and MS. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades or analytical packages are available to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2R,3S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.