Description

5-Acetyl-2-Amino-4-(4-Methoxyphenyl)-6-Methyl-4H-Pyran-3-Carbonitrile is a high-value, multi-functional heterocyclic building block with a complex pyran core structure. This compound matters for its role as a critical synthetic intermediate in the development of advanced pharmaceutical and agrochemical active ingredients. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Dye & Pigment Synthesis: Employed in the creation of novel chromophores and functional dyes due to its conjugated system and electron-donating/accepting groups.
• Academic & Contract Research: Essential for methodological studies in organic synthesis, heterocyclic chemistry, and medicinal chemistry within university and CRO laboratories.
• Custom Synthesis & Scale-Up: A starting point for contract manufacturing organizations (CMOs) engaged in producing bespoke fine chemicals for client projects.

Basic Information

Product Name	5-Acetyl-2-Amino-4-(4-Methoxyphenyl)-6-Methyl-4H-Pyran-3-Carbonitrile
CAS No.	105263-07-8
Molecular Formula	C16H16N2O3
Molecular Weight	284.31 g/mol
Synonyms	5-Acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile; 4H-Pyran-3-carbonitrile, 5-acetyl-2-amino-4-(4-methoxyphenyl)-6-methyl-; 2-Amino-5-acetyl-4-(4-methoxyphenyl)-6-methyl-4H-pyran-3-carbonitrile; 3-Cyano-5-acetyl-2-amino-4-(p-methoxyphenyl)-6-methyl-4H-pyran; KRP-1 (research code); AAMPC
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Amino-4-(4-Methoxyphenyl)-6-Methyl-4H-Pyran-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.