Description

Methyl 15-[(Trimethylsilyl)Oxy]Abieta-8,11,13-Trien-18-Oate CAS NO 104857-68-3 is a functionalized abietane diterpenoid derivative, specifically a silyl-protected methyl ester. This compound is a key synthetic intermediate valued for its role in modifying the core abietane skeleton, which is of significant interest in pharmaceutical and advanced material research. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel bioactive molecules and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel diterpenoid-based drug candidates, including potential anti-inflammatory, antimicrobial, or anticancer agents.
• Agrochemical Research: Used in the development of new plant protection agents and growth regulators, leveraging the bioactivity of the modified abietane structure.
• Organic Synthesis: Acts as a protected intermediate in multi-step synthetic routes, where the trimethylsilyl (TMS) group provides stability and controls reactivity for subsequent transformations.
• Material Science: Investigated as a precursor for functional polymers or liquid crystals due to its rigid, polycyclic core and derivatizable functional groups.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex, resinous, or woody odorants and flavor compounds derived from diterpene backbones.
• Academic & R&D: Employed in university and corporate research laboratories for mechanistic studies, methodology development, and exploring new chemical space.

Basic Information

Product Name	Methyl 15-[(Trimethylsilyl)Oxy]Abieta-8,11,13-Trien-18-Oate
CAS No.	104857-68-3
Molecular Formula	C24H38O3Si
Molecular Weight	402.64 g/mol
Synonyms	Methyl 15-(trimethylsilyloxy)abieta-8,11,13-trien-18-oate; 15-[(Trimethylsilyl)oxy]abieta-8,11,13-trien-18-oic acid methyl ester; Methyl 15-(TMS-oxy)abietate derivative; Abietic acid methyl ester, 15-(trimethylsilyl) ether; 15-Trimethylsilyloxyabietic acid methyl ester; TMS-protected methyl abietate; Methyl 15-hydroxyabietate TMS ether
EINECS	Contact for details

Quality Control

Our Methyl 15-[(Trimethylsilyl)Oxy]Abieta-8,11,13-Trien-18-Oate is produced under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. While specific grades can be tailored, our standard material typically meets research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC or GC), and impurity profile is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.