Description

Cyclohexanecarboxamide, 4-[(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Methyl]- is a high-purity specialty chemical building block featuring a reactive maleimide group tethered to a cyclohexane carboxamide core. This compound matters for its role as a key intermediate in the synthesis of advanced polymers, pharmaceutical candidates, and materials requiring specific cross-linking or conjugation capabilities. Industrial and R&D professionals in pharmaceutical development, polymer science, and advanced material manufacturing need this product for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring maleimide-based conjugation for targeted drug delivery or linker chemistry.
• Polymer & Resin Modification: Used to introduce reactive maleimide sites into polymer backbones or coatings, enabling subsequent cross-linking, grafting, or property enhancement for specialty adhesives, composites, and high-performance films.
• Bioconjugation Reagent: Acts as a linker molecule for attaching peptides, proteins, or other biomolecules to surfaces, nanoparticles, or other carriers via thiol-maleimide "click" chemistry.
• Advanced Material Research: Employed in R&D for developing novel functional materials, such as self-healing polymers, smart hydrogels, and liquid crystal displays, where precise molecular architecture is crucial.
• Cross-linking Agent: Functions as a cross-linker in the formulation of thermosetting resins, elastomers, and specialty coatings to improve thermal stability, mechanical strength, and chemical resistance.
• Chemical Synthesis Intermediate: Provides a versatile synthon for organic chemists to construct more complex heterocyclic and alicyclic compounds for various industrial applications.

Basic Information

Item	Details
Product Name	Cyclohexanecarboxamide, 4-[(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Methyl]-
CAS No.	104676-09-7
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	4-(Maleimidomethyl)cyclohexanecarboxamide; N-(4-Maleimidomethylcyclohexyl)formamide; 1-(4-Carbamoylcyclohexyl)methyl-1H-pyrrole-2,5-dione; 4-(Maleimidomethyl)cyclohexanecarboxylic acid amide; Maleimidomethylcyclohexanecarboxamide; 4-Maleimidomethyl-cyclohexanecarboxamide; 1-[(4-Carbamoylcyclohexyl)methyl]-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxamide, 4-[(2,5-Dihydro-2,5-Dioxo-1H-Pyrrol-1-Yl)Methyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the stringent requirements of pharmaceutical and advanced material industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.