Description

(2Rs,3Rs)-3,5,7-Trihydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydro-4H-Chromen-4-One CAS NO 104486-98-8 is a high-purity, stereochemically defined dihydroflavonol compound. This specific enantiomer is valued for its precise biological activity and serves as a critical reference standard and advanced pharmaceutical intermediate. It is essential for research and development in the pharmaceutical, nutraceutical, and fine chemical sectors, where exact stereochemistry and purity are paramount for efficacy and regulatory compliance.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of flavonoid-based drugs and natural products in HPLC, LC-MS, and NMR methods.
• Active Pharmaceutical Ingredient (API) Intermediate: A key chiral building block in the synthesis of advanced therapeutic agents targeting oxidative stress and inflammation.
• Nutraceutical & Cosmetic Research: Investigated for its potent antioxidant and skin-protective properties in high-end cosmetic formulations and dietary supplements.
• Biochemical Research: Serves as a precise tool for studying enzyme inhibition, receptor binding, and metabolic pathways related to flavonoid activity.
• Quality Control & Standardization: Employed to standardize and authenticate botanical extracts and herbal preparations in compliance with pharmacopeial monographs.

Basic Information

Product Name	(2Rs,3Rs)-3,5,7-Trihydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydro-4H-Chromen-4-One
CAS No.	104486-98-8
Molecular Formula	C15H12O6
Molecular Weight	288.25 g/mol
Synonyms	(2R,3R)-Dihydroquercetin; (2R,3R)-Taxifolin; (2R,3R)-3,5,7,3',4'-Pentahydroxyflavanone; (2R,3R)-3,3',4',5,7-Pentahydroxyflavanone; (2R,3R)-trans-Dihydroquercetin; (+)-Taxifolin; trans-Taxifolin; Aromadendrin
EINECS	Contact for details

Quality Control

Our (2Rs,3Rs)-3,5,7-Trihydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydro-4H-Chromen-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (2R,3R enantiomer)
Loss on Drying	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.