Description

(S)-(+)-2-Methylbutyl Methanesulfonate CAS NO 104418-40-8 is a high-purity chiral building block and alkylating agent, essential for introducing the (S)-2-methylbutyl moiety into complex molecular architectures. Its value lies in its role as a key intermediate for the enantioselective synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop optically pure products.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of enantiomerically pure APIs, particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereochemistry can significantly impact biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Chemistry: Employed in the synthesis of complex, naturally-derived flavor and aroma compounds where stereochemistry defines the organoleptic properties.
• Material Science Research: Acts as a monomer or functionalization agent in the development of chiral polymers and advanced functional materials.
• Process Chemistry & Scale-up: Used in route development and optimization for the commercial manufacturing of high-value chiral compounds.

Basic Information

Product Name	(S)-(+)-2-Methylbutyl Methanesulfonate
CAS No.	104418-40-8
Molecular Formula	C7H16O3S
Molecular Weight	180.27 g/mol
Synonyms	(S)-2-Methylbutyl Methanesulfonate; (S)-(+)-2-Methyl-1-butyl Methanesulfonate; (S)-1-Methanesulfonyloxy-2-methylbutane; (S)-2-Methylbutyl Mesylate; L-2-Methylbutyl Methanesulfonate; (S)-(-)-2-Methylbutyl Methanesulfonate (enantiomer); Methanesulfonic acid (S)-2-methylbutyl ester
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Methylbutyl Methanesulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profiles are provided for every shipment, ensuring full traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (Assay by GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.