Description

(1R)-(-)-(10-Camphorsulfonyl)Oxaziridine is a high-purity, chiral oxaziridine reagent derived from camphorsulfonic acid. This compound is a powerful and selective oxidizing agent, valued for its ability to facilitate asymmetric oxygen transfer reactions under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of chiral sulfoxides, epoxidation, and other stereoselective transformations.

Application

• Asymmetric Synthesis: Key reagent for the enantioselective oxidation of sulfides to sulfoxides, a critical step in producing chiral active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediates: Used in the synthesis of complex drug molecules requiring high stereochemical purity, such as proton pump inhibitors.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and flavors & fragrances where precise stereocontrol is necessary.
• Academic & Process R&D: A valuable tool for chemists developing new catalytic cycles and stereoselective methodologies in laboratory and pilot-scale research.
• Chiral Auxiliary & Catalyst: Functions as a stoichiometric chiral oxidant or can be incorporated into catalyst systems for asymmetric epoxidation reactions.

Basic Information

Product Name	(1R)-(-)-(10-Camphorsulfonyl)Oxaziridine
CAS No.	104372-31-8
Molecular Formula	C10H15NO3S
Molecular Weight	229.30 g/mol
Synonyms	(-)-(1R)-(-)-(10-Camphorsulfonyl)oxaziridine; (R)-(-)-Camphorsulfonyl Oxaziridine; (1R)-10-Camphorsulfonyloxaziridine; (R)-10-(Camphorsulfonyl)oxaziridine; (R)-CSO; Davis Reagent; Chiral Davis Oxaziridine; (+)-(7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl Oxaziridine (enantiomer)
EINECS	Contact for details

Quality Control

Our (1R)-(-)-(10-Camphorsulfonyl)Oxaziridine is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through comprehensive analytical techniques including HPLC, chiral chromatography, and NMR. A Certificate of Analysis (COA) detailing purity, chiral purity, and identity is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.