Description

Ethyl4-(Acetylthio)Butyrate is a specialized sulfur-containing ester compound with the CAS number 104228-51-5. This chemical serves as a valuable building block and intermediate in advanced organic synthesis, particularly for introducing thioester functional groups. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or requiring specific sulfur-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the thioester moiety can contribute to biological activity.
• Flavor & Fragrance Industry: Acts as an intermediate for creating complex sulfur-containing aroma compounds that contribute to savory, roasted, or meaty notes.
• Material Science Research: Employed in the development of novel polymers or functional materials where the acetylthio group can be used for further chemical modification or cross-linking.
• Bioconjugation Chemistry: Useful as a reagent for modifying proteins, peptides, or other biomolecules through thiol-reactive chemistry.
• Organic Synthesis Reagent: Serves as a versatile reagent for introducing protected thiol groups or for use in Michael addition reactions and other C-S bond-forming transformations.

Basic Information

Product Name	Ethyl4-(Acetylthio)Butyrate
CAS No.	104228-51-5
Molecular Formula	C8H14O3S
Molecular Weight	190.26 g/mol
Synonyms	Ethyl 4-(Acetylthio)butyrate; 4-(Acetylthio)butyric Acid Ethyl Ester; Ethyl 4-Acetylthiobutanoate; Butanoic acid, 4-(acetylthio)-, ethyl ester; Acetylthiobutyric Acid Ethyl Ester; NSC 405124; Ethyl γ-(Acetylthio)butyrate
EINECS	Contact for details

Quality Control

Our Ethyl4-(Acetylthio)Butyrate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.470 - 1.480
Density	1.10 - 1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.