Description

(2S,3S)-2-Amino-3-Methoxybutanoic Acid is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at two chiral centers. This compound matters as a sophisticated chiral building block, enabling the synthesis of complex molecules with precise three-dimensional structures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and advanced chemical probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) to incorporate a methoxy-substituted amino acid residue, modifying peptide backbone properties and biological activity.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in catalytic asymmetric reactions to construct other enantiomerically pure compounds.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate amino acid metabolism and enzyme specificity.
• Ligand Development: Useful for creating novel chelating agents or ligands for metal catalysis and molecular recognition applications.
• Material Science: Potential monomer for synthesizing specialized polymers with unique structural and functional properties.

Basic Information

Product Name	(2S,3S)-2-Amino-3-Methoxybutanoic Acid
CAS No.	104195-80-4
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(2S,3S)-2-Amino-3-methoxybutyric acid; (2S,3S)-3-Methoxy-2-aminobutanoic acid; L-threo-3-Methoxy-2-aminobutanoic acid; (2S,3S)-3-Methoxy-DL-threonine; 3-Methoxy-L-threonine; 2-Amino-3-methoxybutanoic acid (S,S-isomer); Amino methoxy butanoic acid; AMBA (S,S)
EINECS	Contact for details

Quality Control

Our (2S,3S)-2-Amino-3-Methoxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.