Description

Grifolan is a biologically active polysaccharide, specifically a (1→3)-β-D-glucan, derived from fungal sources. This compound is valued for its potent immunomodulatory and antitumor properties, making it a key subject of research in pharmaceutical and nutraceutical development. It is primarily utilized by researchers and manufacturers in the fields of immunology, oncology, and functional food ingredients.

Application

• Immunology Research: Used as a model compound to study macrophage activation, cytokine production, and innate immune response modulation.
• Anticancer Agent Development: Investigated for its ability to inhibit tumor growth and metastasis through immune system stimulation.
• Adjuvant Formulation: Explored as a potential vaccine adjuvant to enhance specific immune responses.
• Nutraceutical & Functional Foods: Incorporated into dietary supplements and health foods aimed at supporting immune function.
• Biomaterial Science: Studied for its gel-forming properties and potential use in drug delivery systems and wound healing applications.
• Comparative Pharmacology: Serves as a reference standard for evaluating the activity of other β-glucans.

Basic Information

Product Name	Grifolan
CAS No.	104074-36-4
Molecular Formula	(C6H10O5)n
Molecular Weight	High molecular weight polymer
Synonyms	Grifolan; GRN; (1→3)-β-D-Glucan from Grifola frondosa; β-Glucan GRN; Grifola frondosa polysaccharide; MD-Fraction related polysaccharide; Maitake D-Fraction component; Antitumor polysaccharide GRN
EINECS	Contact for details

Quality Control

Our Grifolan is produced under strict quality management protocols. Each batch is characterized for its polysaccharide profile, purity, and biological activity. A comprehensive Certificate of Analysis (COA) is provided, detailing specifications for identification, assay, endotoxin levels, and microbiological limits to ensure suitability for research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (as β-Glucan)	≥ 90.0%
Protein Content	≤ 5.0%
Moisture Content (KF)	≤ 8.0%
pH (1% solution)	5.0 - 7.0
Endotoxin	< 10.0 EU/mg
Total Microbial Count	< 1000 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.