Description

4-Bromobutyltrifluoromethanesulfonate is a versatile and highly reactive alkylating agent, specifically a bromoalkyl triflate. This compound is valued for its dual-leaving group capability, making it an essential intermediate for introducing the 4-bromobutyl moiety into complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing key carbon chains and functionalizing target molecules with high precision and efficiency.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating alkyl linkers for prodrugs or targeted therapeutics.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require specific bromoalkyl side chains.
• Ligand and Catalyst Development: Employed in organometallic chemistry to functionalize phosphines, amines, and other ligands for catalytic systems.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce reactive bromo groups into polymer backbones for further derivatization.
• Material Science Research: Utilized in surface functionalization and the creation of self-assembled monolayers (SAMs) on various substrates.
• Organic Synthesis Reagent: Acts as a robust electrophile in nucleophilic substitution reactions (SN2) to install butyl chains terminated with a versatile bromine handle.

Basic Information

Product Name	4-Bromobutyltrifluoromethanesulfonate
CAS No.	103935-49-5
Molecular Formula	C5H8BrF3O3S
Molecular Weight	285.08 g/mol
Synonyms	4-Bromobutyl Triflate; 1-Bromo-4-(trifluoromethanesulfonyloxy)butane; Trifluoromethanesulfonic Acid 4-Bromobutyl Ester; 4-Bromobutyl Trifluoromethanesulfonate; Butane, 1-bromo-4-[(trifluoromethyl)sulfonyl]oxy]-; 4-Bromo-1-butanol Triflate; 4-Bromobutyl Trifluoromethylsulfonate
EINECS	Contact for details

Quality Control

Our production of 4-Bromobutyltrifluoromethanesulfonate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability due to its moisture-sensitive and light-sensitive nature. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.