Description

5-Hydroxy-2-[[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Methyl]-4H-Pyran-4-One is a valuable protected derivative of kojic acid, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in its role as a key building block for the synthesis of more complex molecules, particularly in pharmaceutical and cosmetic research. This compound is essential for R&D chemists and process development scientists working in fine chemical, pharmaceutical, and specialty chemical manufacturing who require high-purity, reliable intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a protected kojic acid moiety.
• Cosmetic Ingredient Synthesis: Used in the research and development of next-generation skin-lightening agents, antioxidants, and anti-aging compounds derived from kojic acid.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and natural product analogs.
• Agrochemical Research: Serves as an intermediate in the development of new fungicides or plant growth regulators that utilize the pyranone structure.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional organic materials.

Basic Information

Product Name	5-Hydroxy-2-[[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Methyl]-4H-Pyran-4-One
CAS No.	103893-45-4
Molecular Formula	C11H14O6
Molecular Weight	242.23 g/mol
Synonyms	5-Hydroxy-2-(tetrahydro-2H-pyran-2-yloxymethyl)-4H-pyran-4-one; Kojic Acid THP Ether; 2-[(Tetrahydro-2H-pyran-2-yloxy)methyl]-5-hydroxy-4H-pyran-4-one; 5-Hydroxy-2-((tetrahydro-2H-pyran-2-yloxy)methyl)-4H-pyran-4-one; Kojic Acid THP Ester; 4H-Pyran-4-one, 5-hydroxy-2-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]-; THP-protected Kojic Acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-[[(Tetrahydro-2H-Pyran-2-Yl)Oxy]Methyl]-4H-Pyran-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can supply material compliant with research-grade and custom synthesis specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.