Description

4-[2-Oxo-3-(2H-Tetrazol-5-Yl)Chromen-6-Yl]Oxybutanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure combining a coumarin core with a tetrazole moiety. This compound is critical for the research and development of novel therapeutic agents, particularly in areas requiring specific molecular scaffolds for biological activity screening. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting enzymes or receptors where the coumarin-tetrazole hybrid structure is pharmacologically relevant.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies to develop new chemical entities with optimized biological profiles.
• Biochemical Probe Development: Acts as a core scaffold for creating fluorescent or active site-directed probes for studying biological processes and target validation.
• Library Synthesis for High-Throughput Screening (HTS): Employed in the generation of diverse compound libraries for screening against novel disease targets.
• Academic & Institutional R&D: Utilized in university and government research labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	4-[2-Oxo-3-(2H-Tetrazol-5-Yl)Chromen-6-Yl]Oxybutanoic Acid
CAS No.	103876-50-2
Molecular Formula	C₁₄H₁₂N₄O₅
Molecular Weight	316.27 g/mol
Synonyms	4-[(2-Oxo-3-(2H-tetrazol-5-yl)-2H-chromen-6-yl)oxy]butanoic acid; 6-(3-Carboxypropoxy)-3-(2H-tetrazol-5-yl)-2H-chromen-2-one; 3-(1H-Tetrazol-5-yl)-6-(3-carboxypropoxy)-2H-chromen-2-one; 4-[3-(1H-Tetrazol-5-yl)-2-oxo-2H-chromen-6-yl]oxybutanoic acid; Tetrazole-coumarin carboxylic acid derivative; Coumarin-tetrazole hybrid acid
EINECS	Contact for details

Quality Control

Our 4-[2-Oxo-3-(2H-Tetrazol-5-Yl)Chromen-6-Yl]Oxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.