Description

(1S)-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine is a chiral, non-racemic amine derivative of tetralin, serving as a critical building block in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional group arrangement, which are essential for creating molecules with specific biological activity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) active drugs, potential serotonin receptor modulators, and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or plant growth regulators where the tetralin scaffold imparts specific biological properties.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a chiral test substrate in the development of new catalytic systems for enantioselective synthesis.
• Fine Chemical Production: Serves as a starting material or intermediate in the multi-step synthesis of complex fragrance molecules, dyes, or other specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(1S)-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine
CAS No.	103834-50-0
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(1S)-5-Methoxy-1,2,3,4-tetrahydro-1-naphthalenamine; (S)-5-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine; (S)-5-Methoxy-1-amino-1,2,3,4-tetrahydronaphthalene; (S)-1-Amino-5-methoxy-1,2,3,4-tetrahydronaphthalene; (S)-5-Methoxy-1-tetralinamine; (1S)-5-Methoxy-1,2,3,4-tetrahydro-1-naphthylamine
EINECS	Contact for details

Quality Control

Our (1S)-5-Methoxy-1,2,3,4-Tetrahydronaphthalen-1-Amine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination, to ensure it meets the stringent requirements for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, enantiomeric purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.