Description

8-Chloro-Chroman-3-Ylamine Hydrochloride is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters as a key chiral building block for the development of complex, biologically active molecules, offering precise structural control. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel therapeutic agents, particularly in the areas of central nervous system (CNS) and cardiovascular research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with chroman-based structures.
• Chiral Building Block: Used in asymmetric synthesis to construct complex molecules with defined stereochemistry for medicinal chemistry applications.
• Agrochemical Research: Serves as a key intermediate in the development of new generation pesticides and herbicides.
• Organic Synthesis: Employed in academic and industrial laboratories for the preparation of specialized chroman derivatives and heterocyclic compounds.
• Chemical Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Chloro-Chroman-3-Ylamine Hydrochloride
CAS No.	103659-78-5
Molecular Formula	C9H11Cl2NO
Molecular Weight	220.10 g/mol
Synonyms	8-Chloro-3,4-dihydro-2H-1-benzopyran-3-amine hydrochloride; 8-Chloro-3-aminochroman hydrochloride; 3-Amino-8-chlorochroman hydrochloride; 8-Chloro-3-chromanamine HCl; 103659-78-5; 8-Chlorochroman-3-ylamine HCl; 8-Chloro-2,3-dihydro-1-benzopyran-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-Chroman-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.