Description

2-Benzyloxybenzylbromide is a versatile brominated aromatic ether compound, serving as a key organic synthetic intermediate. Its primary value lies in its reactivity as a benzyl bromide derivative, enabling efficient alkylation and functional group transformations in complex molecule construction. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing diaryl ether or benzyl-protected phenol motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators requiring specific aromatic ether linkages.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands, N-heterocyclic carbene (NHC) precursors, and other organocatalysts.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for the preparation of tagged molecules and bioconjugation reagents in proteomics and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Benzyloxybenzylbromide
CAS No.	103633-30-3
Molecular Formula	C₁₄H₁₃BrO
Molecular Weight	277.16 g/mol
Synonyms	1-(Benzyloxy)-2-(bromomethyl)benzene; (2-(Benzyloxy)phenyl)methyl bromide; o-Benzyloxybenzyl bromide; 2-(Bromomethyl)phenyl benzyl ether; α-Bromo-2-(benzyloxy)toluene; Bromomethyl phenyl benzyl ether; Benzyl 2-(bromomethyl)phenyl ether
EINECS	Contact for details

Quality Control

Our 2-Benzyloxybenzylbromide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.