Description

2,4(1H,3H)-Pyrimidinedione, 1,3-Dimethyl-5-(Tributylstannyl)- is a specialized organotin derivative of a dimethyluracil core, serving as a critical synthetic intermediate. This compound matters for its unique reactivity, enabling precise carbon-tin bond formation in complex molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analogs and other bioactive molecules for drug discovery programs.
• Stille Coupling Reagent: Acts as a versatile organotin reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, essential for constructing complex organic frameworks.
• Material Science Research: Used in the development of functionalized polymers and organic electronic materials where precise molecular architecture is required.
• Chemical Biology Probe Synthesis: Facilitates the labeling and modification of biomolecules for mechanistic studies and diagnostic applications.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of high-value fine chemicals.

Basic Information

Item	Detail
Product Name	2,4(1H,3H)-Pyrimidinedione, 1,3-Dimethyl-5-(Tributylstannyl)-
CAS No.	103408-63-5
Molecular Formula	C18H34N2O2Sn
Molecular Weight	429.18 g/mol
Synonyms	5-(Tributylstannyl)-1,3-dimethyluracil; 1,3-Dimethyl-5-(tributylstannyl)uracil; 1,3-Dimethyl-5-tributylstannyl-2,4(1H,3H)-pyrimidinedione; Tributyl(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)stannane; Uracil, 5-(tributylstannyl)-1,3-dimethyl-; 5-(Tributylstannyl)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and heavy metals are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the organotin content and light-sensitive nature, handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Tin (Sn) Content	27.0 - 28.5 %
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.