Description

7-Fluoro-2,2-Dimethyl-3,4-Dihydro-2H-1,4-Benzoxazin-3-One is a high-purity fluorinated benzoxazinone derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in enabling the precise construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique fluorinated heterocyclic scaffold.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom and benzoxazinone core can enhance biological activity and environmental stability.
• Organic Synthesis Building Block: Employed in medicinal chemistry and process R&D for constructing complex heterocyclic frameworks via reactions such as cyclizations, cross-couplings, and functional group transformations.
• Material Science Precursor: Investigated for the synthesis of specialty polymers, dyes, and photoactive materials that require fluorinated aromatic components.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and chemical manufacturing.

Basic Information

Product Name	7-Fluoro-2,2-Dimethyl-3,4-Dihydro-2H-1,4-Benzoxazin-3-One
CAS No.	103362-10-3
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	7-Fluoro-2,2-dimethyl-2H-1,4-benzoxazin-3(4H)-one; 2H-1,4-Benzoxazin-3(4H)-one, 7-fluoro-2,2-dimethyl-; 7-Fluoro-2,2-dimethyl-4H-1,4-benzoxazin-3-one; 7-Fluoro-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-one; 103362-10-3; Fluorinated benzoxazinone; 7-Fluoro-2,2-dimethyl-1,4-benzoxazin-3-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2,2-Dimethyl-3,4-Dihydro-2H-1,4-Benzoxazin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.