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3-Bromo-4-(tert-Butyl)Aniline CAS NO 103275-21-4


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CAS No.:103275-21-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-4-(tert-Butyl)Aniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the introduction of both bromine and a bulky tert-butyl group onto an aromatic amine scaffold. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the bromine atom and tert-butyl group contribute to biological activity and metabolic stability.
  • Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
  • Functional Material Precursor: Employed in the production of advanced polymers, dyes, and pigments, where its structural features impart specific electronic or steric properties.
  • Organic Synthesis Building Block: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization to create complex molecular architectures.

Basic Information

Product Name 3-Bromo-4-(tert-Butyl)Aniline
CAS No. 103275-21-4
Molecular Formula C10H14BrN
Molecular Weight 228.13 g/mol
Synonyms 3-Bromo-4-tert-butylaniline; 4-(tert-Butyl)-3-bromoaniline; 3-Bromo-4-(1,1-dimethylethyl)benzenamine; 1-Amino-2-bromo-5-tert-butylbenzene; Benzenamine, 3-bromo-4-(1,1-dimethylethyl)-; 3-Bromo-4-tert-butylphenylamine; 3-Br-4-t-Bu-aniline
EINECS Contact for details

Quality Control

Our 3-Bromo-4-(tert-Butyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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