Description

1-Boc-3-(Toluene-4-Sulfonyloxy)-Pyrrolidine is a high-purity, protected pyrrolidine derivative designed for advanced organic synthesis. This compound serves as a critical versatile building block for constructing complex nitrogen-containing heterocycles, enabling precise molecular modifications. It is primarily utilized by pharmaceutical research and development teams, agrochemical scientists, and specialty chemical manufacturers who require reliable, high-quality intermediates for their synthetic workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Peptidomimetic Chemistry: Used to introduce constrained pyrrolidine scaffolds into peptide backbones to enhance stability and biological activity.
• Agrochemical Synthesis: Employed in the development of novel herbicides and fungicides that contain functionalized pyrrolidine rings.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Scale-up: An essential intermediate for contract research organizations (CROs) and CDMOs offering custom synthesis services from milligram to kilogram scale.

Basic Information

Product Name	1-Boc-3-(Toluene-4-Sulfonyloxy)-Pyrrolidine
CAS No.	103057-45-0
Molecular Formula	C16H23NO5S
Molecular Weight	341.42 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-[(4-methylphenyl)sulfonyl]oxy]pyrrolidine; 3-[(4-Methylbenzenesulfonyl)oxy]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-3-(4-Toluenesulfonyloxy)pyrrolidine; tert-Butyl 3-((tosyl)oxy)pyrrolidine-1-carboxylate; N-Boc-3-tosyloxypyrrolidine; 1-Boc-3-OTs-pyrrolidine; Pyrrolidine, 1-[(1,1-dimethylethoxy)carbonyl]-3-[(4-methylphenyl)sulfonyl]oxy]-
EINECS	Contact for details

Quality Control

Our 1-Boc-3-(Toluene-4-Sulfonyloxy)-Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.