Description

2'-Deoxyadenylyl(3'5')-2'-*Deoxyadenosin E Ammonium is a high-purity dinucleotide derivative, specifically a deoxyadenosine dimer, supplied as an ammonium salt. This compound is a critical building block and reference standard in advanced life science research and pharmaceutical development. It is essential for researchers and manufacturers working in oligonucleotide synthesis, molecular biology, and the development of nucleic acid-based therapeutics.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite precursor or intermediate in the solid-phase synthesis of DNA sequences.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving polymerases, nucleases, and other DNA-modifying enzymes.
• Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in the production of antisense oligonucleotides and other nucleic acid drugs.
• Diagnostic Probe Development: Utilized in the design and calibration of sensitive DNA probes for molecular diagnostics and genetic testing.
• Academic Research: Fundamental tool for studying DNA structure, stability, and hybridization kinetics in university and institutional laboratories.

Basic Information

Item	Detail
Product Name	2'-Deoxyadenylyl(3'5')-2'-*Deoxyadenosin E Ammonium
CAS No.	102783-52-8
Molecular Formula	C20H28N10O10P • xNH3
Molecular Weight	Contact for details
Synonyms	d(ApA) ammonium salt; Deoxyadenylyl-(3'→5')-deoxyadenosine ammonium salt; Adenine dinucleotide deoxy- ammonium; 2'-Deoxyadenylyl-(3'-5')-2'-deoxyadenosine ammonium; d(ApA) NH4+ salt; pd(A-A) ammonium; Deoxyadenosine dimer ammonium salt; dA(3'-5')dA ammonium
EINECS	Contact for details

Quality Control

Our 2'-Deoxyadenylyl(3'5')-2'-*Deoxyadenosin E Ammonium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for moisture and endotoxin levels where applicable. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.