Description

Poly(n-Isopropylacrylamide-n-tert-Butylacrylamide)Copolymer is a synthetic, temperature-responsive polymer known for its sharp lower critical solution temperature (LCST) behavior in aqueous solutions. This property makes it a critical material for developing smart, stimuli-responsive systems in advanced research and industrial applications. It is primarily sought after by researchers and formulators in the biomedical, pharmaceutical, and materials science sectors for applications requiring precise thermal control.

Application

• Drug Delivery Systems: As a key component in thermosensitive hydrogels for controlled release of active pharmaceutical ingredients.
• Biomedical Research: For cell sheet engineering and tissue culture where non-enzymatic cell detachment is required.
• Smart Materials & Sensors: In the fabrication of actuators, valves, or optical sensors that respond to temperature changes.
• Separation Technology: Utilized in affinity precipitation and chromatography for the purification of biomolecules.
• Cosmetic Formulations: As a viscosity modifier or gelation agent in products designed to change texture upon application to skin.
• Advanced Coatings: For creating surfaces with switchable wettability or adhesion properties.

Basic Information

Product Name	Poly(n-Isopropylacrylamide-n-tert-Butylacrylamide)Copolymer
CAS No.	102667-59-4
Molecular Formula	(C6H11NO)x(C7H12NO)y
Molecular Weight	Variable (Polymer)
Synonyms	Poly(NIPAM-co-tBAAm); PNIPAM-co-PtBAAm; Poly(N-isopropylacrylamide-co-N-tert-butylacrylamide); Thermoresponsive NIPAM-tBAAm Copolymer; PNIPAAm-co-PtBAAm; Smart Polymer; LCST Polymer; N-Isopropylacrylamide / N-tert-Butylacrylamide Copolymer
EINECS	Contact for details

Quality Control

Our Poly(n-Isopropylacrylamide-n-tert-Butylacrylamide)Copolymer is manufactured under a strict quality management system. Each batch is characterized for critical parameters including monomer ratio, molecular weight distribution, and LCST to ensure batch-to-batch consistency for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, composition, and performance data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Composition (NIPAM:tBAAm Ratio)	As per customer requirement (e.g., 90:10, 80:20)
Number Average Molecular Weight (Mn)	5 kDa - 200 kDa (Customizable)
Polydispersity Index (PDI)	< 1.5
Lower Critical Solution Temperature (LCST)	20°C - 40°C (Tunable based on ratio)
Residual Monomer (HPLC)	< 0.5%
Loss on Drying	< 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.