Description

Tetrahydro-2H-Pyran-3-Ylacetic Acid is a versatile chiral building block and intermediate in organic synthesis. Its value lies in its functionalized pyran ring and acetic acid side chain, which are crucial for constructing complex molecular architectures. This compound is primarily needed by pharmaceutical, agrochemical, and fine chemical research and development teams for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure contributes to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Tetrahydro-2H-Pyran-3-Ylacetic Acid
CAS No.	102539-71-9
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	3-(Carboxymethyl)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-3-acetic acid; 3-Pyranacetic acid, tetrahydro-; 2H-Pyran-3-acetic acid, tetrahydro-; 102539-71-9; (Tetrahydro-2H-pyran-3-yl)acetic acid; 3-(Carboxymethyl)oxane
EINECS	Contact for details

Quality Control

Our Tetrahydro-2H-Pyran-3-Ylacetic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.