Description

Cyclopropanecarboxamide, 2-(Trimethylsilyl)- (9Ci) is a high-value organosilicon building block featuring a reactive amide group and a cyclopropane ring. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the cyclopropane moiety is prized for its unique conformational and biological properties. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs) containing cyclopropane rings, which are common in antiviral, anticancer, and CNS-targeting drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the cyclopropane structure can enhance biological activity and stability.
• Organometallic & Catalysis: Serves as a ligand precursor or a modifying agent in transition metal catalysis and organometallic chemistry research.
• Material Science: Building block for specialty polymers and advanced materials requiring silicon-functionalized components.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in methodological development and exploratory chemistry for creating new carbon-silicon and carbon-carbon bonds.

Basic Information

Product Name	Cyclopropanecarboxamide, 2-(Trimethylsilyl)- (9Ci)
CAS No.	102488-86-8
Molecular Formula	C7H15NOSi
Molecular Weight	157.29 g/mol
Synonyms	2-(Trimethylsilyl)cyclopropanecarboxamide; 2-Trimethylsilylcyclopropanecarboxamide; Cyclopropanecarboxamide, 2-(trimethylsilyl)-; 2-(Trimethylsilyl)cyclopropanecarboxylic acid amide; 2-(Trimethylsilyl)cyclopropanecarboxylic acid, amide; 102488-86-8; 2-TMS-cyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxamide, 2-(Trimethylsilyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications. We operate under a cGMP-compliant quality system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.