Description

1-o-(Dihydroxymethylsilyl)-β-D-Mannopyranuronic Acid CAS NO 102397-69-3 is a specialized organosilicon-modified carbohydrate derivative, representing a unique class of functionalized sugars. This compound is valued for its bifunctional nature, combining the hydrophilic, chiral backbone of a uronic acid with the reactive silyl group, enabling its use as a sophisticated linker or precursor in advanced material synthesis. It is primarily sought by research and development teams in the pharmaceutical, biotechnology, and advanced materials sectors for applications requiring precise molecular modification and surface functionalization.

Application

• Bioconjugation & Drug Delivery: Serves as a versatile linker for attaching therapeutic agents, peptides, or targeting moieties to nanoparticles, polymers, or solid supports due to its reactive silyl and carboxylic acid groups.
• Surface Modification & Silanization: Used to functionalize glass, silica, or metal oxide surfaces, imparting a hydrophilic, carbohydrate-based layer that can resist non-specific protein adsorption or enable further covalent coupling.
• Advanced Material Synthesis: Acts as a key monomer or cross-linking agent in the development of novel hydrogels, biocompatible polymers, and smart materials with tailored degradation profiles.
• Chiral Stationary Phases: Employed in the development of high-performance liquid chromatography (HPLC) columns for the enantiomeric separation of complex pharmaceutical compounds.
• Glycochemistry Research: A critical intermediate in the synthetic pathway for creating complex glycoconjugates, neoglycoproteins, and other biologically active carbohydrate mimics.
• Diagnostic Assays: Utilized in the fabrication of biosensor surfaces and diagnostic platforms where a stable, biologically relevant interface is required.

Basic Information

Item	Details
Product Name	1-o-(Dihydroxymethylsilyl)-β-D-Mannopyranuronic Acid
CAS No.	102397-69-3
Molecular Formula	C9H16O9Si
Molecular Weight	296.30 g/mol
Synonyms	1-O-(Dihydroxymethylsilyl)-β-D-mannopyranuronic acid; β-D-Mannopyranuronic acid, 1-O-(dihydroxymethylsilyl)-; Dihydroxymethylsilyl β-D-mannopyranuronate; (Dihydroxymethylsilyl) mannuronic acid; Silylated mannuronic acid; Organosilicon carbohydrate; CAS 102397-69-3
EINECS	Contact for details

Quality Control

Every batch of 1-o-(Dihydroxymethylsilyl)-β-D-Mannopyranuronic Acid is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with data from NMR (1H, 13C, 29Si), HPLC, and mass spectrometry to confirm identity, purity, and consistency. Our quality systems are designed to support research and cGMP-grade requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.