Description

2-Chloro-2-(4-Chlorophenyl)Acetic Acid is a versatile chlorinated aromatic acid derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid group and two chlorine atoms on adjacent carbons, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators, leveraging its chlorinated phenylacetic acid backbone.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring a substituted phenylacetic acid structure.
• Academic & Industrial Research: A valuable reagent for method development and exploring new reaction pathways in organic synthesis laboratories.

Basic Information

Product Name	2-Chloro-2-(4-Chlorophenyl)Acetic Acid
CAS No.	102333-77-7
Molecular Formula	C8H6Cl2O2
Molecular Weight	205.04 g/mol
Synonyms	(4-Chlorophenyl)(chloro)acetic acid; 2-Chloro-2-(4-chlorophenyl)ethanoic acid; α-Chloro-4-chlorophenylacetic acid; 4-Chloro-α-chlorophenylacetic acid; p-Chloro-α-chlorophenylacetic acid; NSC 406916; (4-Chlorophenyl)chloroacetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-2-(4-Chlorophenyl)Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.