Description

2-Bromo-1-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)Ethanone is a high-purity, specialized brominated ketone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique benzo[d][1,3]dioxin core structure makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for complex synthesis and R&D programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromoacetyl group for further functionalization.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes due to its electrophilic carbonyl and bromide moieties.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis, including cross-coupling reactions and heterocycle formation.
• Ligand & Catalyst Development: Used as a precursor for synthesizing complex chelating ligands and organocatalysts.

Basic Information

Item	Details
Product Name	2-Bromo-1-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)Ethanone
CAS No.	102293-80-1
Molecular Formula	C₁₂H₁₃BrO₃
Molecular Weight	285.14 g/mol
Synonyms	6-Acetyl-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one, 2-Bromo; 2-Bromo-1-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)ethanone; 2,2-Dimethyl-6-(2-bromoacetyl)-4H-1,3-benzodioxin-4-one; 6-(2-Bromoacetyl)-2,2-dimethyl-4H-1,3-benzodioxin-4-one; 2-Bromo-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(2,2-Dimethyl-4H-Benzo[D][1,3]Dioxin-6-Yl)Ethanone is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.