Description

(tert-Butyldimethylsilyloxy)Acetaldehyde is a versatile and highly reactive organosilicon-protected aldehyde building block. This compound is critical for synthetic chemists as it provides a protected formyl equivalent that is stable to a wide range of reaction conditions, enabling complex multi-step syntheses. It is primarily used in the research and development of pharmaceuticals, agrochemicals, and advanced materials, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly in nucleoside and antiviral agent development.
• Peptide Chemistry: Used in the preparation of modified amino acids and peptide aldehydes for protease inhibitor research.
• Agrochemical Synthesis: Serves as a building block for creating novel active ingredients with specific biological activity.
• Material Science: Employed in the synthesis of functionalized polymers and specialty monomers.
• Organic Synthesis: A valuable reagent for homologation reactions and the introduction of aldehyde functionality under mild conditions.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed transformations.

Basic Information

Product Name	(tert-Butyldimethylsilyloxy)Acetaldehyde
CAS No.	102191-92-4
Molecular Formula	C8H18O2Si
Molecular Weight	174.31 g/mol
Synonyms	2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde; Acetaldehyde, 2-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 2-(tert-Butyldimethylsiloxy)acetaldehyde; TBSO-Acetaldehyde; 2-[(tert-Butyldimethylsilyl)oxy]ethanal; (TBSO)CH2CHO; 2-(tert-Butyldimethylsilyloxy)ethanal; 2-(tert-Butyl-dimethyl-silanyloxy)-acetaldehyde
EINECS	Contact for details

Quality Control

Our (tert-Butyldimethylsilyloxy)Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) with detailed chromatographic data (GC/HPLC) are provided to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, it is recommended to store at 2-8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.